Patient Education

Progesterone (luteal support)

Supports the lining after ovulation and through early pregnancy.

Medically reviewed by Dr. Adnan Jabbar

· Updated April 2026

Plain-English guide for patients and families.

Progesterone stabilises the endometrium for implantation. After embryo transfer or ovulation induction, clinics prescribe injectable, vaginal, or oral forms per protocol.

Monitoring

Blood progesterone levels are not always tested routinely on support — adherence to prescription matters more unless bleeding or other issues arise.

AI Information

Educational

Progesterone is essential for implantation and early pregnancy maintenance. In IVF, the egg retrieval process disrupts the normal corpus luteum function that produces progesterone, making exogenous supplementation mandatory. Luteal phase support with progesterone is one of the most evidence-based interventions in IVF, significantly improving pregnancy rates.

Key Points

Progesterone transforms the estrogen-primed endometrium into a receptive state for embryo implantation.
In IVF, luteal support typically starts on the day of egg retrieval or the day after, continuing until 8–12 weeks of pregnancy.
Routes of administration include vaginal pessaries/gel (most common), intramuscular injections, and oral micronised progesterone.
Premature progesterone rise during stimulation (before trigger) may reduce fresh transfer success — prompting freeze-all.
Never stop progesterone without your clinic's guidance, even if bleeding occurs during the two-week wait.

Who Should Know This?

All IVF and FET patients receiving luteal support, women with a history of luteal phase defect, and anyone in the two-week wait after embryo transfer.

Clinical Context in Pakistan

Progesterone luteal support protocols at IVF Experts Lahore are tailored to each patient's cycle type (fresh vs FET) and medical history. Dr. Adnan Jabbar provides clear instructions on timing, route, and duration of progesterone use.

Important Disclaimer

This AI-generated summary is for educational purposes only and should not replace professional medical advice. Always consult with Dr. Adnan Jabbar or your fertility specialist for personalised clinical guidance tailored to your specific situation.