IVF Experts
Tissue-Specific Regeneration

Precision Repair for
Reproductive Tissue.

Multipotent stem cells exist naturally within every tissue in the body — including the endometrium, ovaries, and testes. Unlike pluripotent cells, they are already partially specialized, making them precise instruments for tissue-specific repair. Dr. Adnan Jabbar harnesses these cells — including ADSCs, endometrial stem cells, and spermatogonial stem cells — for targeted reproductive regeneration.

Explore Multipotent Therapies
Multipotent Stem Cell Research

Targeted, Not Unlimited

Multipotent cells differentiate only into related tissue types — making them safer and more predictable than pluripotent cells for clinical use.

Multipotent Stem Cells in Reproductive Medicine

Each reproductive organ harbors its own population of resident stem cells that maintain and regenerate tissue throughout life.

Endometrial Stem Cells

The endometrium regenerates completely every menstrual cycle — powered by resident endometrial stem/progenitor cells in the basalis layer. These cells can be isolated and used to repair damaged endometrium.

Applications: Thin endometrium, Asherman's Syndrome, recurrent implantation failure

Ovarian Surface Epithelial Cells

Controversial but promising: some research suggests the ovarian surface epithelium contains ovarian stem cells (OSCs) capable of generating new oocytes — challenging the dogma that women are born with a fixed egg count.

Applications: POF, diminished ovarian reserve (research phase)

Spermatogonial Stem Cells (SSCs)

SSCs reside in the seminiferous tubules and are responsible for lifelong sperm production. They can be isolated, preserved, and re-transplanted — particularly valuable for fertility preservation before chemotherapy.

Applications: Pre-chemo preservation, testicular failure, post-cancer recovery

Adipose-Derived (ADSCs)

The workhorses of clinical stem cell therapy. Harvested from fat tissue via mini-liposuction. The most accessible and well-studied multipotent cells for reproductive applications.

Full ADSC details →

Bone Marrow-Derived

BM-derived stem cells have been shown to home to damaged reproductive organs when systemically administered. They contribute to endometrial repair and have shown ovarian regenerative potential in animal models.

Applications: Systemic reproductive repair, endometrial regeneration

Menstrual Blood-Derived

A non-invasive source: menstrual blood contains endometrial stem cells that can be collected painlessly. Research shows they can differentiate into functional endometrial tissue and other cell types.

Advantage: Non-invasive collection, no surgical harvest needed

Multipotent vs. Pluripotent: Key Differences

FeatureMultipotentPluripotent
DifferentiationLimited to related tissue typesAny cell type in the body
Clinical AvailabilityAvailable nowResearch phase
Safety ProfileExcellent — low tumorigenic riskRequires careful monitoring
ExamplesADSCs, MSCs, SSCsiPSCs, ESCs
SourcePatient's own tissueReprogrammed cells / embryos

Research & Clinical Partners

Multipotent stem cell research and clinical protocols at Dr. Adnan Jabbar's practice are developed in collaboration with Sakina International Hospital and The University of Lahore.

FAQs About Multipotent Stem Cells

Are multipotent stem cells safer than pluripotent?

Generally yes. Because they have limited differentiation potential, the risk of uncontrolled growth (teratoma formation) is significantly lower. This is why ADSCs and MSCs are the predominant stem cells used in current clinical practice.

Can spermatogonial stem cells be frozen for future use?

Yes. SSC cryopreservation before chemotherapy is being developed as a fertility preservation strategy, particularly for pre-pubertal boys who cannot produce mature sperm for freezing. After cancer remission, the SSCs would be re-transplanted.

Which multipotent stem cell is best for fertility?

ADSCs are currently the most widely used due to easy harvesting, high cell yield, and strong clinical evidence. MSCs from Wharton's Jelly are preferred for immunomodulatory applications. The choice depends on the specific clinical situation.

Precision-targeted repair.

Multipotent stem cells are the clinically available, safe, and effective tools of regenerative fertility medicine today.

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