Regenerative Gynecology

Reawakening
Dormant Follicles.

Q: Is ovarian stem cell therapy safe?

Autologous stem cells carry zero immunological rejection risk. The procedure is minimally invasive with no reported carcinogenic risks.

Q: What is the difference between Ovarian PRP and Stem Cell therapy?

PRP provides a burst of growth factors from platelets. Stem cells provide sustained multi-modal regeneration. Dr. Adnan Jabbar often combines both.

Q: Who is a good candidate for ovarian rejuvenation?

Women with low AMH, diminished ovarian reserve, POI, poor IVF response, or those who wish to try their own eggs before donor eggs. Age under 45 provides the best outcomes.

When low AMH and primary ovarian failure signal the end of natural fertility, stem cell and PRP-based ovarian rejuvenation offers a revolutionary pathway. Dr. Adnan Jabbar is pioneering these cutting-edge regenerative protocols in Lahore, Pakistan — aiming to reactivate primordial follicles and restore ovarian function where conventional medicine has reached its limits.

Explore Rejuvenation Options Stem Cell Center →

Stem Cell Ovarian Rejuvenation by Dr. Adnan Jabbar

The Regenerative Revolution

Growth factors from stem cells and PRP can penetrate the ovarian cortex, reactivating dormant primordial follicles that standard IVF cannot reach.

How Ovarian Rejuvenation Works

Even in women diagnosed with "depleted" ovarian reserve, the ovarian cortex may harbor dormant primordial follicles that standard gonadotropin stimulation simply cannot activate. Stem cell and PRP-based rejuvenation works by creating a molecularly enriched microenvironment that kickstarts these sleeping follicles.

Growth Factor Cascade: VEGF restores blood supply, IGF-1 promotes granulosa cell survival, EGF triggers follicle recruitment from the dormant pool.
Anti-Fibrotic Action: Stem cells release anti-inflammatory cytokines that dissolve scar tissue within the aging ovarian cortex, creating physical space for follicle growth.
Exosome Signaling: Stem cell-derived exosomes carry mRNA and microRNA that reprogram aged granulosa cells, restoring their ability to support egg maturation.

Rejuvenation Protocols at Our Clinic

Ovarian PRP Injection

Platelet-Rich Plasma concentrated from the patient's own blood is injected directly into the ovarian cortex under ultrasound guidance. The concentrated growth factors stimulate local follicle recruitment.

ADSC Ovarian Injection

Adipose-Derived Stem Cells harvested via mini-liposuction are processed and injected into the ovaries, providing sustained paracrine stimulation far more potent than PRP alone.

MSC / Exosome Therapy

Mesenchymal stem cell-derived exosomes deliver targeted molecular signals to repair the ovarian niche, with early data showing AMH improvements in 40-60% of patients.

What Patients Can Expect

Rejuvenation timelines and realistic expectations based on current clinical data.

2-4

Weeks

Initial hormonal changes may begin to appear on blood work (rising estradiol, slight AMH increase).

2-3

Months

Ultrasound may reveal new antral follicles developing. Menstrual cycles may resume in amenorrheic patients.

3-6

Months

Optimal window for IVF stimulation. Follicles recruited by stem cells/PRP are now mature enough for retrieval.

40-60%

Response Rate

Published data shows measurable ovarian response in 40-60% of treated patients with DOR/POI.

Dr. Adnan Jabbar: Leading Ovarian Rejuvenation in Pakistan

While stem cell-based ovarian rejuvenation remains at the frontier of reproductive medicine globally, Dr. Adnan Jabbar is one of the very few specialists in Pakistan actively offering these protocols. His integrated approach combines Ovarian PRP with ADSC injection and subsequent tailored IVF stimulation — giving women with extremely low AMH and premature ovarian failure a fighting chance at biological motherhood. His clinic in Lahore has become a destination for patients who have been turned away by conventional fertility centers across Pakistan.

Frequently Asked Questions About Stem Cell Ovarian Rejuvenation

Is ovarian stem cell therapy safe?

When using autologous stem cells (from the patient's own fat tissue), there is zero risk of immunological rejection. The procedure is minimally invasive, performed under light sedation, with minimal recovery time. No carcinogenic risks have been reported in clinical studies to date.

What is the difference between Ovarian PRP and Stem Cell therapy?

PRP is derived from blood platelets and provides a concentrated burst of growth factors. Stem cells (ADSCs/MSCs) provide a more sustained, multi-modal regenerative effect including paracrine signaling, exosome release, and potential cellular replacement. Dr. Adnan Jabbar often combines both for maximum impact.

Who is a good candidate for ovarian rejuvenation?

Women with low AMH (<1.0 ng/mL), diminished ovarian reserve, premature ovarian insufficiency (POI), poor IVF response, or those who wish to try conception with their own eggs before resorting to donor eggs. Age under 45 generally provides the best outcomes.

Reawakening Dormant Follicles.